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golfguysgirl
06-23-2007, 02:14 PM
...multiple sclerosis?

Inigo Montoya
06-23-2007, 02:36 PM
Amyotrophic lateral sclerosisAmyotrophic lateral sclerosis (ALS) is a neurological disorder characterized by progressive degeneration of motor neuron cells in the spinal cord and brain, which ultimately results in paralysis and death. The disease takes its less-scientific name from Lou Gehrig, a baseball player with the New York Yankees in the late 1920s and 1930s, who was forced to retire in 1939 as a result of the loss of motor control caused by the disease. In 1991, a team of researchers linked familial ALS to chromosome 21. Two years later, the SOD1 gene was identified as being associated with many cases of familial ALS. The enzyme coded for by SOD1 carries out a very important function in cells: it removes dangerous superoxide radicals by converting them into non-harmful substances. Defects in the action of this enzyme mean that the superoxide radicals attack cells from the inside, causing their death. Several different mutations in this enzyme all result in ALS, making the exact molecular cause of the disease difficult to ascertain.Recent research has suggested that treatment with drugs called antioxidants may benefit ALS patients. However, since the molecular genetics of the disease are still unclear, a significant amount of research is still required to design other promising treatments for ALS

www.ncbi.nlm.nih.gov (http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowSection&rid=gnd.section.194)

sailing_orienteer
06-23-2007, 02:43 PM
This is the "differential diagnosis" section of the emedicine write-up on Multiple Sclerosis. (See source web page below.) Conditions listed under differential diagnosis usually have overlapping symptoms. "DIFFERENTIALS Section 4 of 11 Amyotrophic Lateral Sclerosis Bell Palsy Brain Abscess Guillain-Barré Syndrome HIV Infection and AIDS Lumbar (Intervertebral) Disk Disorders Neck Trauma Sarcoidosis Spinal Cord Infections Spinal Cord Injuries Stroke, Hemorrhagic Stroke, Ischemic Subdural Hematoma Syphilis Systemic Lupus Erythematosus Tick-Borne Diseases, Lyme Transient Ischemic Attack Trigeminal Neuralgia Other Problems to be Considered: Behçet diseaseBrainstem tumorsCentral nervous system infectionsCerebellar tumorsFriedreich ataxiaHereditary ataxiasLeukodystrophiesNeurofibromatosisPernicious anemiaProgressive multifocal leukoencephalopathyRuptured intervertebral diskSmall cerebral infarctsSpinal cord tumorsSyringomyeliaVasculitides"

www.emedicine.com (http://www.emedicine.com/emerg/topic321.htm)