Heart Failure?

[pss4dm]

How could you categorise the effects of heart failure on skeletal muscle dysfunction, i.e structural changes, metabolic pathways.What headings could all the changes be placed under. Im writing a project and need to place each individual change into its own grouping.

[abh]

i dont think there r any structural changes in skeletal musclebut since O2 delivery is hampered there is more of anaerobic cellular respiration leading to mild lactic acidosis causing fatigue & weakness

[white skull]

I found this..but don't know when it was updated last..http://cpmcnet.columbia.edu/news/in-vivo/Vol2_Iss07_apr09_03/this is done on rates...I don't know ...I hope it would be helpfullhttp://www.medscape.com/medline/abstract/7484170this is the most recent I found...."Vascular rarefaction in peripheral skeletal muscle after experimental heart failure "http://ajpheart.physiology.org/cgi/content/abstract/285/4/H1554good luck